{"id":60296,"date":"2016-04-01T10:21:35","date_gmt":"2016-04-01T10:21:35","guid":{"rendered":"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/medical-and-clinical-biophysics\/research\/laboratory-equipment\/"},"modified":"2023-10-25T11:13:58","modified_gmt":"2023-10-25T10:13:58","slug":"laboratory-equipment","status":"publish","type":"cpt_ustav","link":"https:\/\/www.upjs.sk\/lekarska-fakulta\/en\/department\/medical-and-clinical-biophysics\/research\/laboratory-equipment\/","title":{"rendered":"Laboratory equipment"},"content":{"rendered":"\n
gilent 6538 Ultra High Definition Accurate Mass Q-TOF<\/strong>\u00a0mass spectrometer is designed to provide superior data quality and advanced analytical capabilities for profiling, identifying, characterizing, and quantifying as low molecular weight compounds as biomolecules with greater confidence. With 5 orders of in-spectrum dynamic range improves detection of trace level targets in the presence of high abundance compounds. Its 40 000 mass resolution capability and fast scan speed distinguishes target analytes from interferences. \u00a0The Q-TOF MS\/MS is unique in its ability to give accurate mass measurements of the fragment ions that are ejected from the collision chamber, which give a high assurance of correct identification of unknowns, as well as an empirical formula of fragment ions. It is coupled to HPLC separation model (Agilent Technologies 1260 Infinity) with capillary and nano pump, which separate peptides before they enter the mass spectrometer. Thanks to special software the data measured are compared with protein databases and final protein identification is achieved.\u00a0<\/p>\n\n\n\n