{"id":28957,"date":"2020-02-06T10:07:36","date_gmt":"2020-02-06T10:07:36","guid":{"rendered":"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/root\/anatomia\/vyskum\/"},"modified":"2023-05-19T10:47:57","modified_gmt":"2023-05-19T09:47:57","slug":"vyskum","status":"publish","type":"cpt_ustav","link":"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/anatomia\/vyskum\/","title":{"rendered":"V\u00fdskum"},"content":{"rendered":"<p><!--\n\n\n<p style=\"text-align: justify;\">Certifik\u00e1t M\u0160VVa\u0160 SR za excelentne realizovan\u00fd a ukon\u010den\u00fd projekt KEGA 3\/7291\/09 (MVDr. Kv\u011btu\u0161e Lov\u00e1sov\u00e1, PhD.)<\/p>\n\n\n\n--><\/p>\n<h3 style=\"text-align: justify;\">Vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 pracoviska je zameran\u00e1 na tieto v\u00fdskumn\u00e9 oblasti:<\/h3>\n<ul>\n<li style=\"text-align: justify;\">\u0160t\u00fadium eduka\u010dn\u00fdch met\u00f3d za \u00fa\u010delom skvalitnenia v\u00fdu\u010dby anat\u00f3mie slovensk\u00fdch aj zahrani\u010dn\u00fdch \u0161tudentov pod\u013ea odpor\u00fa\u010dania odborn\u00edkov Eur\u00f3pskej \u00fanie. Ide o aktu\u00e1lnu po\u017eiadavku s\u00fa\u010dasnosti nielen pre n\u00e1ro\u010dnos\u0165 osvojenia si vedomost\u00ed z&nbsp;anat\u00f3mie, ale aj pre koordin\u00e1ciu pr\u00edstupov pri v\u00fdu\u010dbe \u0161tudentov v&nbsp;slovenskom a&nbsp;v anglickom jazyku. Cie\u013eom je d\u00f4kladn\u00e9 poznanie z\u00e1kladn\u00fdch \u0161trukt\u00far \u013eudsk\u00e9ho tela s implement\u00e1ciou ich v\u00fdznamnosti v medic\u00ednskej praxi.<\/li>\n<li style=\"text-align: justify;\">Rie\u0161enie problematiky mozgovo-kompatibiln\u00e9ho u\u010denia, ktor\u00e9 sa zaober\u00e1 mo\u017enos\u0165ami efekt\u00edvneho u\u010denia s vyu\u017eit\u00edm najnov\u0161\u00edch poznatkov o mozgu. Hlavn\u00fdm cie\u013eom projektu je nau\u010di\u0165 \u0161tudenta u\u010di\u0165 sa &nbsp;tak, aby \u010do najlep\u0161ie vyu\u017eil potenci\u00e1l svojho mozgu, tr\u00e1vil&nbsp;u\u010den\u00edm&nbsp;menej \u010dasu a&nbsp; uchoval poznatky v dlhodobej pam\u00e4ti.<\/li>\n<li style=\"text-align: justify;\">Pr\u00edprava komplexnej vysoko\u0161kolskej u\u010debnice (\u0161tudijn\u00e9ho materi\u00e1lu) so zakomponovan\u00edm ultrasonografie do praktickej v\u00fdu\u010dby anat\u00f3mie \u2013 korel\u00e1cia anatomick\u00e9ho a ultrasonografick\u00e9ho obrazu org\u00e1nov a \u0161trukt\u00far za fyziologick\u00e9ho stavu. V\u00fdsledok \u2013 \u00fazke prepojenie teoretick\u00e9ho predmetu anat\u00f3mia s klinickou praxou, konkr\u00e9tne s ultrasonografick\u00fdm vy\u0161etren\u00edm, ktor\u00e9 je dnes neoddelite\u013enou s\u00fa\u010das\u0165ou z\u00e1kladn\u00fdch vy\u0161etrovac\u00edch met\u00f3d v mnoh\u00fdch medic\u00ednskych odboroch.<\/li>\n<li style=\"text-align: justify;\">\u0160t\u00fadium vybran\u00fdch prote\u00ednov ako mo\u017en\u00fdch predikt\u00edvnych, ale aj prognostick\u00fdch biomarkerov v&nbsp;s\u00favislosti s&nbsp;karcin\u00f3mom prsn\u00edka. V\u00fdskum je zameran\u00fd na&nbsp;\u03b2III-tubul\u00edn,&nbsp;karbonick\u00fa anhydr\u00e1zu IX, p53 a&nbsp;survivin. Ako experiment\u00e1lny model sa pou\u017e\u00edva chemicky indukovan\u00fd karcin\u00f3m mlie\u010dnej \u017e\u013eazy u&nbsp;sam\u00edc potkana, ktor\u00e9 s\u00fa n\u00e1sledne lie\u010den\u00e9 paclitaxelom a&nbsp;doxorubic\u00ednom. Expresia t\u00fdchto prote\u00ednov\u00fdch markerov je sledovan\u00e1 pred a&nbsp;po cytostatickej lie\u010dbe. Na stanovenie hlad\u00edn vybran\u00fdch prote\u00ednov v&nbsp;n\u00e1dorovom&nbsp;&nbsp;tkanive je pou\u017e\u00edvan\u00e1 imunohistochemick\u00e1 met\u00f3da. Na hodnotenie expresie prote\u00ednov v&nbsp;perif\u00e9rnej krvi sa vyu\u017e\u00edva met\u00f3da ELISA.<\/li>\n<li style=\"text-align: justify;\">\u0160t\u00fadium v\u00fdskytu antioxida\u010dn\u00fdch enz\u00fdmov glutati\u00f3nperoxid\u00e1z u experiment\u00e1lnych zvierat.&nbsp;V\u00fdskum je zameran\u00fd na zistenie pr\u00edtomnosti t\u00fdchto enz\u00fdmov v pohlavn\u00fdch org\u00e1noch a&nbsp;v preimplanta\u010dn\u00fdch embry\u00e1ch sam\u00edc potkanov a ich pr\u00edpadn\u00fd vplyv na vznik infertility.<\/li>\n<li style=\"text-align: justify;\"> \u0160t\u00fadium vplyvu kr\u00e1tkodob\u00e9ho a dlhodob\u00e9ho pod\u00e1vania entacapone, inhib\u00edtora COMT, na aktivitu antioxida\u010dn\u00fdch enz\u00fdmov a na ukazovatele oxida\u010dn\u00e9ho stresu v organizme experiment\u00e1lnych zvierat. Cie\u013eom v\u00fdskumu je zisti\u0165 zmeny v hladin\u00e1ch pohlavn\u00fdch horm\u00f3nov a zmeny v reproduk\u010dn\u00fdch parametroch samcov potkana.<\/li>\n<li style=\"text-align: justify;\">\u00dastav anat\u00f3mie spolupracuje s \u010fal\u0161\u00edmi \u00fastavmi LF UPJ\u0160, \u00dastavom histol\u00f3gie a&nbsp;embryol\u00f3gie Jesseniovej lek\u00e1rskej fakulty UK a&nbsp;Neurobiologick\u00fdm \u00fastavom SAV.<\/li>\n<\/ul>\n","protected":false},"author":1,"featured_media":0,"parent":28878,"menu_order":3,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[],"tax_aktuality":[],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>V\u00fdskum - Lek\u00e1rska fakulta | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/anatomia\/vyskum\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"V\u00fdskum - Lek\u00e1rska fakulta | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"Vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 pracoviska je zameran\u00e1 na tieto v\u00fdskumn\u00e9 oblasti: \u0160t\u00fadium eduka\u010dn\u00fdch met\u00f3d za \u00fa\u010delom skvalitnenia v\u00fdu\u010dby anat\u00f3mie slovensk\u00fdch aj zahrani\u010dn\u00fdch \u0161tudentov pod\u013ea odpor\u00fa\u010dania odborn\u00edkov Eur\u00f3pskej \u00fanie. 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