{"id":29277,"date":"2022-05-18T12:33:36","date_gmt":"2022-05-18T12:33:36","guid":{"rendered":"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/root\/histologia-a-embryologia\/vyskum\/"},"modified":"2023-05-30T12:54:45","modified_gmt":"2023-05-30T11:54:45","slug":"vyskum","status":"publish","type":"cpt_ustav","link":"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/histologia-a-embryologia\/vyskum\/","title":{"rendered":"V\u00fdskum"},"content":{"rendered":"<p style=\"text-align:justify\">Od roku 1961 po n\u00e1stupe prof. MUDr. Jozefa Mar\u0161alu, DrSc. za prednostu \u00fastavu, sa vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 preorientovala na experiment\u00e1lnu neuromorfol\u00f3giu. Od roku 1970, v r\u00e1mci celo\u0161t\u00e1tneho rie\u0161enia cerebrovaskul\u00e1rnej problematiky, kolekt\u00edv \u00fastavu rie\u0161il v\u00fdskumn\u00fa \u00falohu \u201eMolekul\u00e1rno-biologick\u00e1 podstata neurovaskul\u00e1rnych vz\u0165ahov\u201c. Na \u00fastave boli rie\u0161en\u00e9 viacer\u00e9 v\u00fdskumn\u00e9 \u00falohy, ktor\u00e9 sa t\u00fdkali regenera\u010dnej schopnosti nervov\u00e9ho tkaniva po jeho isch\u00e9mii a reperf\u00fazii.<\/p>\n<p style=\"text-align:justify\">V rokoch 1986-2019 bolo na na\u0161om pracovisku schv\u00e1len\u00e9 experiment\u00e1lne morfologick\u00e9 laborat\u00f3rium, \u010d\u00edm bola umo\u017enen\u00e1 vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 zamestnancom, ale aj doktorandom a \u0161tudentom LF UPJ\u0160 v r\u00e1mci \u0160VO\u010c. Po z\u00edskan\u00ed grantov a ich schv\u00e1len\u00ed \u0161t\u00e1tnou veterin\u00e1rnou spr\u00e1vou boli v experiment\u00e1lnom morfologickom laborat\u00f3riu realizovan\u00e9 mikrochirurgick\u00e9 z\u00e1kroky na laborat\u00f3rnych zvierat\u00e1ch. Vedecko-v\u00fdskumn\u00e9 v\u00fdsledky boli prezentovan\u00e9 okrem dom\u00e1cich podujat\u00ed aj na zahrani\u010dn\u00fdch kongresoch a publikovan\u00e9 v zahrani\u010dn\u00fdch \u010dasopisoch registrovan\u00fdch v datab\u00e1zach Scopus a Web of Science.<\/p>\n<p style=\"text-align:justify\">Od roku 2005 sa na \u00dastave histol\u00f3gie a embryol\u00f3gie pod veden\u00edm prof. MVDr. Mikul\u00e1\u0161a Pomfyho, CSc., doc. MVDr. \u0160tefana T\u00f3tha, PhD. a prof. MUDr. Evy Mech\u00edrovej, CSc. zapojilo do \u0160VO\u010c aj 24 slovensk\u00fdch a zahrani\u010dn\u00fdch \u0161tudentov. \u0160tyria \u0161tudenti z\u00edskali ocenenie \u201e\u0160tudentsk\u00e1 osobnos\u0165 Slovenska\u201c z r\u00fak prezidenta Slovenskej republiky za mimoriadne v\u00fdsledky v \u0161tudijnej a vedecko-v\u00fdskumnej oblasti po\u010das svojho \u0161t\u00fadia.<\/p>\n<h3>Moderniz\u00e1cia laborat\u00f3ri\u00ed a v\u00fdu\u010dbov\u00fdch priestorov<\/h3>\n<p style=\"text-align:justify\">V rokoch 2007-2008 sa na \u00dastave histol\u00f3gie a embryol\u00f3gie vytvorili podmienky pre vybudovanie laborat\u00f3ria molekulovej biol\u00f3gie s pr\u00edstrojov\u00fdm vybaven\u00edm umo\u017e\u0148uj\u00facim detekciu expresie g\u00e9nov, izol\u00e1ciu RNA, synt\u00e9zu cDNA a kvantifik\u00e1ciu g\u00e9nov \u2013 Real time PCR.<\/p>\n<p style=\"text-align:justify\">\u00dastav histol\u00f3gie a embryol\u00f3gie v\u0161ak potreboval celkov\u00fa rekon\u0161trukciu a moderniz\u00e1ciu priestorov. T\u00e1to prestavba sa uskuto\u010dnila v dvoch etap\u00e1ch. V prvej v roku 2016, z finan\u010dn\u00fdch prostriedkov LF UPJ\u0160, za v\u0161estrannej podpory dekana LF UPJ\u0160 prof. MUDr. Daniela Pellu, PhD. sa zrekon\u0161truovali a zmodernizovali 2 laborat\u00f3ria svetelnej mikroskopie, 1 praktik\u00e1re\u0148 so 16 mikroskopmi a multimedi\u00e1lnou projekciou a spolo\u010dn\u00e9 priestory a pracovne u\u010dite\u013eov na \u00fastave. V roku 2019 sa prednostke \u00fastavu prof. MUDr. Eve Mech\u00edrovej, CSc. podarilo z\u00edska\u0165 nov\u00e9 priestory, v ktor\u00fdch sa po celkovej rekon\u0161trukcii vybudovali \u010fal\u0161ie 2 nov\u00e9 modern\u00e9 praktik\u00e1rne na v\u00fdu\u010dbu \u0161tudentov, vybaven\u00e9 \u0161tudentsk\u00fdmi mikroskopmi a ve\u013ekoplo\u0161n\u00fdmi obrazovkami na prenos mikroskopick\u00e9ho obrazu z kamery mikroskopu. Kamerov\u00fd syst\u00e9m a softv\u00e9r umo\u017e\u0148uje nielen uklada\u0165 mikroskopick\u00e9 sn\u00edmky, ale vykon\u00e1va\u0165 aj merania. Z pozorovan\u00fdch prepar\u00e1tov je mo\u017en\u00e9 vytvori\u0165 video z\u00e1znam. V s\u00fa\u010dasnosti n\u00e1\u0161 \u00fastav disponuje 4 praktik\u00e1r\u0148ami a 2 semin\u00e1rnymi miestnos\u0165ami s dataprojektormi a v\u00fdpo\u010dtovou technikou, \u010do v\u00fdrazne zv\u00fd\u0161ilo kvalitu v\u00fdu\u010dby a odb\u00farala sa praktick\u00e1 v\u00fdu\u010dba \u0161tudentov do ve\u010dern\u00fdch hod\u00edn.<\/p>\n<p style=\"text-align:justify\">V zmodernizovan\u00fdch laborat\u00f3ri\u00e1ch sa spracov\u00e1va materi\u00e1l so z\u00e1kladn\u00fdmi histologick\u00fdmi a histochemick\u00fdmi met\u00f3dami. Pre \u00fa\u010dely v\u00fdskumn\u00fdch projektov vyu\u017e\u00edvame \u0161irok\u00fa \u0161k\u00e1lu imunohistochemick\u00fdch met\u00f3d pre sveteln\u00fa aj fluorescen\u010dn\u00fa mikroskopiu.<\/p>\n<p style=\"text-align:justify\"><strong><a href=\"https:\/\/www.upjs.sk\/public\/media\/9481\/A.%20Specialne%20farbiace%20metody.pdf\">A. Preh\u013ead \u0161peci\u00e1lnych farbiacich a impregna\u010dn\u00fdch met\u00f3d<\/a><br \/>\n<a href=\"https:\/\/www.upjs.sk\/public\/media\/9481\/B.%20Imunohistochemicke%20metody.pdf\">B. Preh\u013ead imunohistochemick\u00fdch met\u00f3d<\/a><\/strong><\/p>\n<h3 style=\"text-align:justify\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/9\/2022\/11\/lmb.png\" style=\"height:297px; width:750px\"><\/h3>\n<h3 style=\"text-align:justify\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/9\/2022\/11\/lim.png\" style=\"height:265px; width:750px\"><\/h3>\n<h3 style=\"text-align:justify\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/9\/2022\/11\/priestory16.png\" style=\"height:469px; width:750px\"><\/h3>\n<p style=\"text-align:justify\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/9\/2022\/11\/priestory20.png\" style=\"height:457px; width:750px\"><\/p>\n<p style=\"text-align:justify\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/9\/2022\/11\/priestory21.png\" style=\"height:458px; width:750px\"><\/p>\n<h3>Vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 \u00fastavu<\/h3>\n<p style=\"text-align:justify\">V s\u00fa\u010dasnosti je vedecko-v\u00fdskumn\u00e1 \u010dinnos\u0165 pracoviska orientovan\u00e1 na tri oblasti:<\/p>\n<ol>\n<li>na problematiku ischemicko-reperf\u00fazneho po\u0161kodenia tenk\u00e9ho \u010dreva v experimente<\/li>\n<li>na problematiku ischemicko-reperf\u00fazneho po\u0161kodenia mozgu a miechy<\/li>\n<li>na d\u00f4kaz alfa- synukle\u00ednu v premotorickom \u0161t\u00e1diu Parkinsonovej choroby.<\/li>\n<\/ol>\n<h3>Organiz\u00e1cia vedeck\u00fdch podujat\u00ed<\/h3>\n<p style=\"text-align:justify\"><strong>Ko\u0161ick\u00fd morfologick\u00fd de\u0148.<\/strong> Od roku 1997 sa ka\u017edoro\u010dne kon\u00e1 stretnutie slovensk\u00fdch morfol\u00f3gov v Ko\u0161iciach, na ktorom sa organiza\u010dne, ka\u017ed\u00fd tret\u00ed rok, podie\u013ea \u00dastav histol\u00f3gie a embryol\u00f3gie UPJ\u0160 LF. Na stretnut\u00ed sa prezentuj\u00fa v\u00fdsledky vedecko-v\u00fdskumnej \u010dinnosti slovensk\u00fdch morfol\u00f3gov a z podujatia je ka\u017edoro\u010dne vydan\u00fd zborn\u00edk vedeck\u00fdch pr\u00e1c.<\/p>\n","protected":false},"author":1,"featured_media":29284,"parent":29235,"menu_order":3,"template":"","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[],"tax_aktuality":[],"class_list":["post-29277","cpt_ustav","type-cpt_ustav","status-publish","has-post-thumbnail","hentry"],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>V\u00fdskum - Lek\u00e1rska fakulta | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/lekarska-fakulta\/ustav\/histologia-a-embryologia\/vyskum\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"V\u00fdskum - Lek\u00e1rska fakulta | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"Od roku 1961 po n\u00e1stupe prof. 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