\n\tPROBIO<\/b> – Probiotick\u00e9 mikroorganizmy a bioakt\u00edvne l\u00e1tky natur\u00e1lneho p\u00f4vodu pre zdrav\u0161iu popul\u00e1ciu Slovenska (26220220104)<\/p>\n
\n\tCEMIO<\/b> – Centrum excelentnosti pre v\u00fdskum faktorov ovplyv\u0148uj\u00facich zdravie so zameran\u00edm na skupinu marginalizovan\u00fdch a imunokompromitovan\u00fdch os\u00f4b (26220120058)<\/p>\n
\n\tPROBIOTECH<\/b> – Kompeten\u010dn\u00e9 centrum pre biomodul\u00e1tory a v\u00fd\u017eivov\u00e9 doplnky (26220220152)<\/p>\n
\n\tDIAGONKO<\/b> – Kompeten\u010dn\u00e9 centrum pre v\u00fdskum a v\u00fdvoj v oblasti diagnostiky a terapie onkologick\u00fdch ochoren\u00ed (26220220153)<\/p>\n
\n\tBIODIAG<\/b> – V\u00fdskumn\u00e9 centrum aplikovanej biomedic\u00ednskej diagnostiky (26220220143)<\/p>\n
\n\tCEEPM<\/b> – Centrum excelentnosti pre elektromagnetick\u00e9 polia v medic\u00edne (26220120067)<\/p>\n
\n\tVERZDRAV<\/b> – V\u00fdskumn\u00e9 centrum modern\u00fdch technol\u00f3gi\u00ed monitorovania a diagnostiky ochoren\u00ed ohrozuj\u00facich verejn\u00e9 zdravie (26220220162)<\/p>\n\n\tRie\u0161en\u00e9 projekty VEGA<\/h3>\n
\n\tVEGA 1\/1204\/94 1994 \u2013 1996:<\/b> \u0160t\u00fadium biologick\u00fdch vlastnost\u00ed gramnegat\u00edvnych ty\u010diniek izolovan\u00fdch od det\u00ed s deficitom imunity pri septick\u00fdch stavoch, meningit\u00eddach a in\u00fdch extraintestin\u00e1lnych infekci\u00e1ch a pri hemolyticko-uremickom syndrome
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Prof. MUDr. Leonard Siegfried, CSc<\/p>\n
\n\tVEGA 1\/6042\/99 1999 – 2003:<\/b> \u0160t\u00fadium rezistencie na antibiotik\u00e1 u bakt\u00e9ri\u00ed izolovan\u00fdch od imunokompromitovan\u00fdch pacientov so zameran\u00edm na beta-laktam\u00e1zy so \u0161irok\u00fdm spektrom
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Prof. MUDr. Leonard Siegfried, CSc<\/p>\n
\n\tVEGA 1\/9317\/02 2002 – 2004:<\/b> Charakteriz\u00e1cia beta-laktam\u00e1z s roz\u0161\u00edren\u00fdm spektrom (ESBL) u klinick\u00fdch kme\u0148ov vybran\u00fdch druhov gramnegat\u00edvnych bakt\u00e9ri\u00ed
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Prof. MUDr. Leonard Siegfried, CSc.<\/p>\n
\n\tVEGA 1\/1203\/04 2004 – 2006:<\/b> Enteropatog\u00e9nne, enteroinvaz\u00edvne, \u0161igatoxig\u00e9nne a in\u00e9 Escherichia coli izolovan\u00e9 pri z\u00e1palov\u00fdch a n\u00e1dorov\u00fdch ochoreniach gastrointestin\u00e1lneho traktu
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Doc. RNDr. Marta Kme\u0165ov\u00e1, CSc.<\/p>\n
\n\tVEGA 1\/2288\/05 2005 – 2007:<\/b> Mechanizmy rezistencie nemocni\u010dn\u00fdch kme\u0148ov gramnegat\u00edvnych pali\u010diek v zdravotn\u00edckych zariadeniach regi\u00f3nu v\u00fdchodn\u00e9ho Slovenska
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Prof. MUDr. Leonard Siegfried, CSc.<\/p>\n
\n\tVEGA 1\/4254\/07 2007 \u2013 2009:<\/b> Detekcia faktorov virulencie v Escherichia coli izolovan\u00fdch pri ochoreniach gastrointerestin\u00e1lneho traktu a mo\u017enosti ich ovplyv\u0148ovania.
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Doc. RNDr. Marta Kme\u0165ov\u00e1, CSc.<\/p>\n
\n\tVEGA 1\/0495\/10 2010 – 2011:<\/b> Virulencia, kolicinog\u00e9nia a fylogenetick\u00e9 skupiny E.coli vo vz\u0165ahu ku klinickej diagn\u00f3ze.
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Doc. RNDr. Marta Kme\u0165ov\u00e1, CSc.<\/p>\n
\n\tVEGA 1\/0857\/10 2010 – 2011:<\/b> S\u00fa\u010dasn\u00e9 poznatky o v\u00fdskyte mechanizmov rezistencie multirezistentn\u00fdch gramnegat\u00edvnych bakt\u00e9ri\u00ed izolovan\u00fdch od pacientov v nemocni\u010dnom a mimonemocni\u010dnom prostred\u00ed
\n\tZodpovedn\u00fd rie\u0161ite\u013e: Prof. MUDr. Leonard Siegfried, CSc.<\/p>\n
\n\tV spolurie\u0161ite\u013estve so SAV: VEGA 2\/0014\/13, 2013 – 2015:<\/b> Funk\u010dn\u00e9 a metabolick\u00e9 vlastnosti kyslomlie\u010dnych bakt\u00e9ri\u00ed tr\u00e1viaceho traktu zvierat.
\n\tZodpovedn\u00fd rie\u0161ite\u013e: RNDr. Dobroslava, Buj\u0148\u00e1kov\u00e1, PhD.,
\n\tZ\u00e1stupca zodpovedn\u00e9ho rie\u0161ite\u013ea z UPJ\u0160-LF: Doc. RNDr. Marta Kme\u0165ov\u00e1, CSc.<\/p>\n\n\tIntern\u00e9 granty<\/h3>\n
\n\t1994 – 1996 – \u0160t\u00fadium prenosnej rezistencie vo\u010di antibiotik\u00e1m u bakteri\u00ed vyvol\u00e1vaj\u00facich infekcie novorodencov<\/p>\n
\n\t2000- 2004 IG3 Biologick\u00e9 vlastnosti bakteri\u00e1lnych kme\u0148ov gastrointestin\u00e1lneho traktu vo vz\u0165ahu k n\u00e1dorov\u00fdm ochoreniam hrub\u00e9ho \u010dreva<\/p>\n
\n\t2002-2004 IG4 LF UPJ\u0160 \u201cIdentifik\u00e1cia kvasiniek rodov Candida, Cryptococcus<\/em> a plesn\u00ed rodu Aspergillus<\/em>, izolovan\u00fdch od imunokompromitovan\u00fdch pacientov met\u00f3dou PCR a ur\u010dovanie ich citlivosti<\/p>\n \n\tOcenenia:<\/u><\/b><\/p>\n \n\tCena LF za najlep\u0161iu p\u00f4vodn\u00fa publik\u00e1ciu LF UPJ\u0160 za rok 1995<\/b> \n\tCena Mikrobiologicko \u2013 epidemiologickej spolo\u010dnosti SLS za najlep\u0161iu publik\u00e1ciu r. 2001<\/b> \n\t1. 1982- 1985 V-3-1\/6<\/b> \u201e\u0160t\u00fadium plazmidov\u00e9ho vybavenia niektor\u00fdch enteropatog\u00e9nov“ \n\t2. 1986- 1990 V- 3-1\/04<\/b> “ \u0160t\u00fadium ETEC a EIEC kme\u0148ov E.coli pri hna\u010dk\u00e1ch mal\u00fdch det\u00ed“. \n\t3. 1986- 1990 VIII- 6-1-1\/07<\/b> “ Inaktiv\u00e1cia mikroorganizmov mechanizmami ne\u0161pecifickej imunity“. \n\t4. 1991-1993 K GAV: 5 1\/99O554\/93<\/b> “ Zis\u0165ovanie zast\u00fapenia kme\u0148ov E.coli a in\u00fdch enterobakt\u00e9ri\u00ed pri mimo\u010drevn\u00fdch infekci\u00e1ch det\u00ed s deficitom imunity. \n\t5. 1994 \u2013 1996 1\/12 04\/94<\/b> OGR pre lek\u00e1rske a farmaceutick\u00e9 vedy „\u0160t\u00fadium biologick\u00fdch vlastnost\u00ed gramnegat\u00edvnych ty\u010diniek izolovan\u00fdch od det\u00ed s deficitom imunity pri septick\u00fdch stavoch, meningit\u00eddach a in\u00fdch extraintestin\u00e1lnych infekci\u00e1ch a pri hemolyticko- uremickom syndr\u00f3me \n\t7.1999- 2001 VEGA projekt \u010d. 1\/6042\/99<\/b> Studium rezistencie na antibiotik\u00e1 u bakt\u00e9ri\u00ed izolovan\u00fdch od imunokompromitovan\u00fdch pacientov so zameran\u00edm na betalaktam\u00e1zy so \u0161irok\u00fdm spektrom \n\t8. VEGA 2002\/2004<\/b> \n\tVEGA 1\/4234\/07<\/b> L.Siegfried- VP K.\u010curov\u00e1- ZVP Vplyv antimikrobi\u00e1lneho peptidu katelicid\u00ednu, Toll-like receptoru 4 a IL-8 na klinick\u00fd priebeh infekcie mo\u010dov\u00fdch ciest sp\u00f4soben\u00fdch uropatog\u00e9nnymi kme\u0148mi Escherichia coli<\/p>\n \n\tVega 1\/0857\/10<\/b> L.Siegfried S\u00fa\u010dasn\u00e9 poznatky o v\u00fdskyte mechanizmov rezistencie multirezistentn\u00fdch gramnegat\u00edvnych bakt\u00e9ri\u00ed izolovan\u00fdch od pacientov v nemocni\u010dnom a mimonemocni\u010dnom prostred\u00ed<\/p>\n \n\t9. 1994- 1996<\/b> 1995 – Projekt v rezorte M\u0160 a V SR \n\t10. hlavn\u00fd rie\u0161ite\u013e in\u0161tituci\u00e1lnej \u00falohy:<\/b> \n\t2000-2002 Spolurie\u0161ite\u013e intern\u00e9ho grantu: IG3 LF UPJ\u0160 \n\t2002-2004 IG4 LF UPJ\u0160 \u201cIdentifik\u00e1cia kvasiniek rodov Candida, Cryptococcus a plesn\u00ed rodu Aspergillus, izolovan\u00fdch od imunokompromitovan\u00fdch pacientov met\u00f3dou PCR a ur\u010dovanie ich citlivosti<\/p>\n \n\tM\u0160 SR-Sekc. vedy a tech. AV 4\/0027\/07<\/b> L.Siegfried- VP Vplyv indolov\u00fdch fytoalex\u00ednov a pro\u00edbiot\u00edk na rast a expresiu faktorov virulencie E.coli izolovan\u00fdch pri z\u00e1palov\u00fdch a n\u00e1dorov\u00fdch ochoreniach \u010driev<\/p>\n \n\t8\/2002\/IGM1<\/b> A.Lipt\u00e1kov\u00e1- VP Sledovanie z\u00e1vislosti expresie shiga tox\u00ednu od p\u00f4sobenia antibiotik<\/p>\n \n\t22\/2002\/<\/b> L.Siegfried- VP Identifik\u00e1cia kvasiniek rodov Candida, Cryptococcus a plesn\u00ed rodu Aspergillus, izolovan\u00fdch od imunokompromitovan\u00fdch pacientov met\u00f3dou PCR a ur\u010dovanie citlivosti k antifung\u00e1lnym l\u00e1tkam<\/p>\n \n\tIG3\/2000-2002<\/b> L.Siegfried- VP Biologick\u00e9 vlastnosti bakteri\u00e1lnych kme\u0148ov gastrointestin\u00e1lneho traktu vo vz\u0165ahu k n\u00e1dorov\u00fdm ochoreniam hrub\u00e9ho \u010dreva<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":29584,"menu_order":2,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[],"tax_aktuality":[],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"\n\n\tNajv\u00fdznamnej\u0161ie vedeck\u00e9 aktivity<\/h3>\n
\n\tSiegfried, L., Kme\u0165ov\u00e1, M., Janigov\u00e1, V., Filka, J.: Serum response of Escherichia coli<\/em> strains causing dyspepsia and urinary tract infection: relation to alpha haemolysin production and O type. Infect. Immun. 63, 1995, s. 4543-4545.<\/p>\n
\n\tKme\u0165ov\u00e1, M., Siegfried, L., Sabol, M., Bogyiov\u00e1, E., \u0160\u00e1ndor\u010dinov\u00e1, Z., Molok\u00e1\u010dov\u00e1, M., Kereste\u0161ov\u00e1, H.: Incidence and transfer of antibiotic resistance in clinical isolates of Escherichia coli<\/em> . Biol\u00f3gia, Bratislava, 56\/5, 2001, s. 55-59.<\/p>\n\n\tRie\u0161en\u00e9 \u00falohy<\/h3>\n
\n\tZodp. rie\u0161. doc. MUDr. H. Puzov\u00e1 CSc.
\n\tSpolurie\u0161itelia: Hlau\u010dov\u00e1 ,J., Kereste\u0161ov\u00e1 ,A., Kme\u0165ov\u00e1, M., \u010eurovi\u010dov\u00e1,, J., Janigov\u00e1 ,V., Sokol, A.:<\/p>\n
\n\tZodp. rie\u0161. doc. MUDr. H. Puzov\u00e1, H., CSc.
\n\tSpolurie\u0161itelia: Hlau\u010dov\u00e1 ,J.,,Kme\u0165ov\u00e1, M., Siegfried, L, Kereste\u0161ov\u00e1, A., \u010eurovi\u010dov\u00e1 , J., Janigov\u00e1 ,V.<\/p>\n
\n\tZodp. rie\u0161. . doc. MUDr. H. Puzov\u00e1 , CSc.
\n\tSpolurie\u0161itelia: Siegfried, L., Hlau\u010dov\u00e1 ,J., Kme\u0165ov\u00e1 ,M., Kereste\u0161ov\u00e1 , A. , \u010eurovi\u010dov\u00e1 , J., Janigov\u00e1 ,V.<\/p>\n
\n\tZodp. rie\u0161. Doc. MUDr. H. Puzov\u00e1, CSc.
\n\tSpolurie\u0161. Siegfried, L., Kme\u0165ov\u00e1 , M., Janigov\u00e1 ,V., \u010eurovi\u010dov\u00e1 , J., Dorko, E., Kereste\u0161ov\u00e1, A.<\/p>\n
\n\tZodp. rie\u0161.projektu Doc. MUDr. L. Siegfried, CSc.,
\n\tZ\u00e1stupca-Doc. Mudr. Puzov\u00e1, H., CSc.,
\n\tSpolurie\u0161.: Kme\u0165ov\u00e1 , M.- z\u00e1stupca , Janigov\u00e1 V., \u010eurovi\u010dov\u00e1, J., Dorko, E.,Kereste\u0161ov\u00e1 , A.<\/p>\n
\n\tZodp. rie\u0161. projektu Doc. MUDr. L. Siegfried, CSc.,
\n\tZ\u00e1stupca: Doc. RNDr. Marta Kme\u0165ov\u00e1, CS.<\/p>\n
\n\tCharakteriz\u00e1cia beta-laktam\u00e1z s roz\u0161\u00edren\u00fdm spektrom (ESBL) u klinick\u00fdch kme\u0148ov vybran\u00fdch druhov gramnegat\u00edvnych bakt\u00e9ri\u00ed
\n\tZodp. rie\u0161.projektu Doc. MUDr. L. Siegfried, CSc.,
\n\tZ\u00e1stupca: Doc. RNDr. Marta Kme\u0165ov\u00e1, CSc.
\n\tSpolurie\u0161.: Sabol. M. , Lipt\u00e1kov\u00e1, A., Heinov\u00e1 Dagmar, Kereste\u0161ov\u00e1 , A.<\/p>\n
\n\tSpolurie\u0161ite\u013e in\u0161titucion\u00e1lnej \u00falohy: \u201c\u0160t\u00fadium prenosnej rezistencie vo\u010di antibiotik\u00e1m u bakt\u00e9ri\u00ed vyvol\u00e1vaj\u00facich infekcie novorodencov\u201d.<\/p>\n
\n\t1997- 1999- Monitorovanie prenosnej rezistencie na antibiotika u gramnegat\u00edvnych bakt\u00e9ri\u00ed na vybran\u00fdch klinick\u00fdch pracovisk\u00e1ch
\n\tVed\u00faci : Doc. RNDr. Marta Kme\u0165ov\u00e1, Csc.<\/p>\n
\n\t\u201cBiologick\u00e9 vlastnosti bakteri\u00e1lnych kme\u0148ov gastrointestin\u00e1lneho traktu vo vz\u0165ahu k n\u00e1dorov\u00fdm ochoreniam hrub\u00e9ho \u010dreva\u201d.<\/p>\n\n\tIn\u00e9 projekty M\u0160 SR<\/h3>\n
\n\tIn\u00e9 granty dom\u00e1ce<\/h3>\n