{"id":14677,"date":"2020-11-25T08:02:22","date_gmt":"2020-11-25T08:02:22","guid":{"rendered":"https:\/\/www.upjs.sk\/pracoviska\/tip\/?page_id=14677"},"modified":"2024-01-29T10:15:11","modified_gmt":"2024-01-29T10:15:11","slug":"actualities-2","status":"publish","type":"page","link":"https:\/\/www.upjs.sk\/pracoviska\/tip\/en\/actualities-2\/","title":{"rendered":"News"},"content":{"rendered":"
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Directed evolution as a tool for developing new molecules in medicine and industry<\/h4>\n <\/a>\n
\n \n Thanks to the accelerated evolution of proteins in the laboratory, we can create useful new molecules that might never have arisen in nature. Nature is a fascinating creator. The evolution of creatures transpires over millions of years. During this time, biological organisms experience transformation and adaptation to their environment. This process, known as natural selection, … Continued<\/a>\n <\/div>\n
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Project ExCasProt<\/h4>\n <\/a>\n
\n \n We are delighted to announce that we have received funding for a new ExCasProt project from the Recovery Plan. This project is a continuation of our successful CasProt project, and its goal is to support the development of biotechnological protein research in Eastern Slovakia. S rados\u0165ou oznamujeme, \u017ee sme z\u00edskali financovanie na nov\u00fd projekt ExCasProt z Pl\u00e1nu … Continued<\/a>\n <\/div>\n
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\n May 28, 2024\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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Merry Christmas and Happy New Year!<\/h4>\n <\/a>\n
\n \n Dear partners and colleagues, dear friends, We would like to thank you for all your collaboration and participation in the activities and ongoing CasProt project. The year 2023 was really fruitful and successful. We could enjoy several events – symposia, out-goings visits, summer schools, on-job trainings \u2013 and work together to solve different scientific issues. … Continued<\/a>\n <\/div>\n
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\n December 20, 2023\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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The CasProt project is over, our scientific ambitions continue<\/h4>\n <\/a>\n
\n \n At the end of September 2023, we have successfully concluded the implementation of the CasProt project, which has significantly contributed to the stabilisation of CIB and its reputation in particular through strengthened collaboration with the partner groups at UZH and TUM. Besides others, the project led to a considerable increase in the impact factor of … Continued<\/a>\n <\/div>\n
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\n September 30, 2023\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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New laboratories for bioscience research<\/h4>\n <\/a>\n
\n \n Rector of P. J. \u0160af\u00e1rik University in Ko\u0161ice (UPJ\u0160), prof. RNDr. Pavol Sov\u00e1k, CSc., Dean of Faculty of Science of UPJ\u0160 (PF UPJ\u0160), doc. RNDr. Roman Sot\u00e1k, PhD. and director of Technology and Innovation Park of UPJ\u0160 (TIP-UPJ\u0160), prof. RNDr. Pavol Mi\u0161kovsk\u00fd, DrSc., ceremoniously opened new laboratories of the renovated spaces localized in the PF … Continued<\/a>\n <\/div>\n
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\n May 18, 2023\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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Ko\u0161ice Region Innovation Awards 2023<\/strong><\/h4>\n <\/a>\n
\n \n The team of the Center for Interdisciplinary Biosciences (CIB) led by Assoc. Prof. Erik Sedl\u00e1k, DrSc. was nominated for the Ko\u0161ice Region Innovation Awards 2023 in cooperation with the Ko\u0161ice Self-governing Region and the founding partners of the association in the category of the best Scientist\/Scientific team of the Ko\u0161ice Region. CIB was nominated for … Continued<\/a>\n <\/div>\n
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Summer school on biophotonics<\/strong><\/h4>\n <\/a>\n
\n \n Summer school on biophotonics was held from May 22nd to 31st 2023 at the Department of Biophysics, Institute of Physics, Faculty of Science of P.J. Safarik University in Kosice. The course aim is to address the task of improving the theoretical as well as practical knowledge of doctoral students in advanced methods of biophotonics. Lectures were … Continued<\/a>\n <\/div>\n
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Summer school on directed evolution of proteins<\/h4>\n <\/a>\n
\n \n Summer School on Directed Evolution of Proteins will take place, for the first time, at Center for Interdisciplinary Biosciences TIP-UPJ\u0160 in Ko\u0161ice in May 2nd \u2013 May 12th 2023. This school will be joint with the Workshop on Directed Evolution of Proteins, where experts will present lectures on protein evolution, design and purification of proteins. Participating students on the Summer … Continued<\/a>\n <\/div>\n
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Workshop on directed evolution of proteins<\/h4>\n <\/a>\n
\n \n Dear colleagues, dear students, we would like to invite you to the Workshop on directed evolution of proteins, which will be held as part of the CasProt project from May 2nd to 5th, 2023 in the seminar room of the Department of Biophysics and the Center for Interdisciplinary Biosciences TIP-UPJ\u0160 at Jesenn\u00e1 5. This 4-day workshop will be devoted … Continued<\/a>\n <\/div>\n
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Symposium on directed evolution of proteins<\/h4>\n <\/a>\n
\n \n The symposium on directed evolution of proteins will take place within the European project CasProt, which was obtained by the scientific groups of the Center for Interdisciplinary Biosciences (CIB) TIP-UPJ\u0160 and the Department of Biophysics (KBF) PF UPJ\u0160 represented by Prof. Pavol Mi\u0161kovsk\u00fd in a consortium with the teams of Prof. Andreas Pl\u00fcckthun from the … Continued<\/a>\n <\/div>\n
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Kick-off meeting on Heme Proteins in Action<\/h4>\n <\/a>\n
\n \n Dolni Brezany, Czech Republic \u2013 On February 20th and 21st, 2023, researchers from ELI Beamlines hosted a kick-off meeting on Heme Proteins in Action. The event was held at ELI Beamlines in Dolni Brezany, Czech Republic; and was attended by experts from Institute of Organic Chemistry, Polish Academy of Sciences (IOC-PAS), Warsaw, Poland; Institute of … Continued<\/a>\n <\/div>\n
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Workshop on single-molecule protein folding<\/h4>\n <\/a>\n
\n \n The Single Molecule Protein Folding Workshop took place from the 13th\u00a0to the 17th\u00a0of March 2023 and was organized as a joint event by Pavol Jozef Safarik University in Kosice, Slovakia (UPJS) and Technical University of Munich, Germany (TUM) in Antholz, Italy. The workshop aimed to bring together experts in the field to discuss various topics … Continued<\/a>\n <\/div>\n
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Casprot researchers revealed morphologies of pathological light chain from multiple myeloma patient<\/h4>\n <\/a>\n
\n \n D\u017eupponov\u00e1 V, \u017dold\u00e1k G. Aggregation mechanism and branched 3D morphologies of pathological human light chain proteins under reducing conditions. Colloids Surf B Biointerfaces. 2023 Jan;221:112983. doi: 10.1016\/j.colsurfb.2022.112983. Multiple myeloma is a hematologic malignancy characterized by a clonal proliferation of plasma cells producing a monoclonal immunoglobulin light chain. Produced monoclonal light chains are then secreted in … Continued<\/a>\n <\/div>\n
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The\u00a0University\u00a0of\u00a0Oxford\u00a0welcomed our PhD student<\/h4>\n <\/a>\n
\n \n Cooperation with the Department of Biochemistry, University of Oxford to develop a new assay to monitor events during protein aggregation at a single-molecule level From the 1st of October to the 20th of December 2022, a PhD student RNDr. Veronika D\u017eupponov\u00e1 (supervisor: Assoc. prof. RNDr. Gabriel \u017dold\u00e1k, PhD.) from the Department of Biophysics UPJ\u0160 in Ko\u0161ice … Continued<\/a>\n <\/div>\n
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On-job trainings of the UPJS administrative staff<\/h4>\n <\/a>\n
\n \n At the end of the 2022 year, the on-job trainings of the UPJS administrative staff were realized to reinforce their management and administrative skills. In total, 7 persons (2 x project managers, 2 x financial managers, 2 x advisors for Horizon Europe projects), mainly from the \u201cProject administrative office\u201d (CCVaPP), but also members from TIP-UPJ\u0160, … Continued<\/a>\n <\/div>\n
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\n December 13, 2022\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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Participation in the 10th Multinational Congress on Microscopy<\/h4>\n <\/a>\n
\n \n Support of the CasProt project gave an opportunity to a member of the Center for Interdisciplinary Biosciences, Veronika Hunto\u0161ov\u00e1, and PhD student, Vikt\u00f3ria Pevn\u00e1, from the Department of Biophysics of UPJ\u0160 in Ko\u0161ice to attend the 16th Multinational Congress on Microscopy (16MCM), which was held in Brno, in the Czech Republic, from 4 to 9 … Continued<\/a>\n <\/div>\n
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Regional Biophysics Conference RBC 2022<\/h4>\n <\/a>\n
\n \n The 9th RBC 2022 Regional Biophysics Conference took place in P\u00e9cs (Hungary) from 22 to 26 August 2022. Thanks to the support of the CasProt project, several employees and PhD students of the Center for Interdisciplinary Biosciences and the Department of Biophysics of UPJ\u0160 in Ko\u0161ice could participate in it actively. The Regional Biophysics Conference … Continued<\/a>\n <\/div>\n
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Attendance at the 21st European Bioenergetics Conference<\/h4>\n <\/a>\n
\n \n Thanks to the support of the CasProt project, Daniel Jancura and a PhD student Adri\u00e1na Tomkov\u00e1 from the Department of Biophysics of UPJ\u0160 in Ko\u0161ice were able to actively participate in the 21st European Bioenergetics Conference which was held at Aix-en-Provence, in France, from 20 to 25 August 2022. The EBEC is a traditional biannual conference … Continued<\/a>\n <\/div>\n
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Summer school on protein stability and folding<\/h4>\n <\/a>\n
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UPJ\u0160 participated in a Symposium on protein stability and folding organized by the CasProt partner in M\u00fcnchen<\/h4>\n <\/a>\n
\n \n A symposium on protein stability and folding was organized in Hohenkammer and Garching b. M\u00fcnchen between 22 and 26 May 2022. In Hohenkammer, in total, 36 talks devoted to current challenges and hot topics in protein science, mainly to forces in biomolecular systems, were presented by invited principal investigators (PI), postdocs and PhD students. Especially, … Continued<\/a>\n <\/div>\n
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Participation in the 5th Instruct Biennial Structural Biology Conference<\/h4>\n <\/a>\n
\n \n Our colleagues, Assoc. prof. Gabriel \u017dold\u00e1k and PhD student Veronika D\u017eupponov\u00e1, participated in the 5th Instruct Biennial Structural Biology Conference, which took place in Utrecht, the Netherlands, from 19 to 20 May 2022. The theme of the 2022 conference was \u201cChanges in Structural Biology: Challenges in Studying Dynamics\u201d. The conference explored new cutting-edge developments in … Continued<\/a>\n <\/div>\n
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UPJ\u0160 organized a symposium of three biomedical projects \u201cTrends in Interdisciplinary Biosciences\u201c<\/h4>\n <\/a>\n
\n \n In mid-January 2022, a scientific symposium entitled “Trends in interdisciplinary biosciences” took place at the Grandhotel Praha in Tatransk\u00e1 Lomnica. This symposium focused on the presentation of the results of three biomedical projects CasProt, BioPickmol and OPENMED funded by the European Commission’s H2020 program and the European Structural and Investment Funds. The main organizer of … Continued<\/a>\n <\/div>\n
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Invitation to the online symposium TRENDS IN INTERDISCIPLINARY BIOSCIENCES 13.1.-15.1.2022<\/h4>\n <\/a>\n
\n \n Technology and Innovation Park UPJ\u0160 invites you to watch the live stream of the symposium of the CasProt, BioPickmol and OPENMED projects entitled TRENDS IN INTERDISCIPLINARY BIO SCIENCES. These are EU-funded research projects in biomedicine, which are implemented in cooperation with Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice and major domestic and European universities, research institutions … Continued<\/a>\n <\/div>\n
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Student from the Department of Biophysics participated in the internship at the Technical University of Munich<\/h4>\n <\/a>\n
\n \n From August to October 2021, a PhD. student of Assoc. Prof. Gabriel \u017dold\u00e1k, Veronika D\u017eupponov\u00e1 from the Department of Biophysics UPJ\u0160 in Ko\u0161ice carried out her study stay at the Technical University of Munich (TUM). The given internship was implemented and financed within Task.1.6. CasProt project and aimed to gain new knowledge and skills in … Continued<\/a>\n <\/div>\n
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An undergraduate student from Nepal joined the CasProt team<\/h4>\n <\/a>\n
\n \n Saroj Neupane, an undergraduate student in Pharmacy from the University in Dhulikhel from Nepal, joined the CasProt team through SAIA NSPS PROGRAM. Saroy comes from Nepal. He joined the team at the end of October 2021 and stays until the end of February 2022. Saroj is working on protein aggregation and stability research. We would … Continued<\/a>\n <\/div>\n
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Meeting of senior researchers and internship of students at University of Zurich<\/h4>\n <\/a>\n
\n \n In August, Assoc. Prof. Erik Sedl\u00e1k made a business trip to Zurich within the Casprot project  as a planned trip in WP1 \u201cOutgoing visits\u201c. During his one month stay in the laboratory of Prof. Andreas Pl\u00fcckthun at the Department of Biochemistry at the University of Zurich, he had several discussions with Prof. Pl\u00fcckhtun and members … Continued<\/a>\n <\/div>\n
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Researchers have developed a matrix for one-step isolation of proteins by affinity chromatography<\/h4>\n <\/a>\n
\n \n As part of the CasProt project, group of Assoc. Prof. Erik Sedl\u00e1k from the Center for Interdisciplinary Biosciences (CIB) from the Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice developed a matrix for one-step isolation of proteins by affinity chromatography in the CIB laboratories in cooperation with the group of Prof. Andreas Pl\u00fcckthun from the University of … Continued<\/a>\n <\/div>\n
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\n October 5, 2021\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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Attendance at the INTERFACES INTERNATIONAL CONFERENCE<\/h4>\n <\/a>\n
\n \n At the end of September, within the CasProt project, Assoc. Prof. Gabriel \u017dold\u00e1k, PhD. made a business trip to the INTERFACES INTERNATIONAL CONFERENCE: From new materials to life science – Structure, Interactions, Dynamics and Activity in Sardinia, Italy. The conference focused on the presentation of the latest knowledge in the field of materials biology, biochemistry … Continued<\/a>\n <\/div>\n
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Participation in the XXVI. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology<\/h4>\n <\/a>\n
\n \n Our colleagues from the CasProt Project – Assoc. Prof. Erik Sedl\u00e1k, Dr. M\u00e1ria Tomkov\u00e1 and Dr. Veronika Talafov\u00e1, participated in the XXVI. Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology with the cooperation of the Austrian and German Biochemical Section which took place in \u010cesk\u00e9 Budejovice, Czech Republic from August 29 … Continued<\/a>\n <\/div>\n
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European Biophysical Conference EBSA 2021<\/h4>\n <\/a>\n
\n \n The 13th EBSA 2021 European Biophysical Conference took place in Vienna (Austria) from 24 to 28 July 2021. Thanks to the support of the CasProt project, several employees and PhD students of the Center for Interdisciplinary Biosciences and the Department of Biophysics of UPJ\u0160 in Ko\u0161ice were able to actively participate in it. EBSA is a … Continued<\/a>\n <\/div>\n
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Top STEDYCON device<\/h4>\n <\/a>\n
\n \n From the 20th to 21st of July 2021, Mr. J. V\u00e1vra, a representative of Abberior GmbH, visited the Laboratory of Advanced Laser Technologies of the Center of Interdisciplinary Biosciences, TIP-UPJ\u0160 in Ko\u0161ice, to lend and install the top STEDYCON device. Abberior GmbH is a German innovative tech company founded by a Nobel Prize winner Prof. … Continued<\/a>\n <\/div>\n
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Enzymatic acceleration cis\/trans proline isomerization in a protein under force discovered by CasProt researchers<\/h4>\n <\/a>\n
\n \n Single-molecule force spectroscopy divulges specific details of how SlyD, a bacterial PPIase, causes a staggering 25-fold acceleration of the trans to cis isomerization of the proline-2225 in an isolated 20th domain of a cytoskeletal mechano-sensing protein, Filamin (FlnA20). SlyD also stabilizes the native-cis state of FlnA20. \u00a0 Prolyl isomerization is recognized as one of the … Continued<\/a>\n <\/div>\n
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Meeting of researchers in Munich<\/h4>\n <\/a>\n
\n \n At the beginning of July, a meeting of researchers from the Department of Biophysics from the Technical University of Munich and the Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice took place in Munich. The meeting was attended by Dr. Abhigyan Sengupta, Dr. Ulrike Majdic, Prof. Matthias Rief from TUM, and Dr. Gabriel \u017dold\u00e1k from UPJ\u0160 in … Continued<\/a>\n <\/div>\n
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Meeting of senior research scientists and the visit of PhD student at Technical University of Munich<\/h4>\n <\/a>\n
\n \n Dr. Gabriel \u017dold\u00e1k made a business trip to Munich within the Casprot project as a planned trip in WP1 \u201cOutgoing visits\u201c from the end of June to the first week of July. The meeting was organized by Prof. Matthias Rief from Technical University in Munich, Germany. They discussed the planned research activities and time schedule … Continued<\/a>\n <\/div>\n
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\n July 13, 2021\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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\n \n \"25172\"\n <\/a>\n <\/div>\n <\/div>\n
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Webinars \u201cSCIENCE MEETS BUSINESS\u201d<\/h4>\n <\/a>\n
\n \n In May and June 2021, three introductory online meetings took place within the series of webinars \u201cSCIENCE MEETS BUSINESS\u201d dedicated to the presentation of the results of basic research and their potential use with the support of the CasProt project. The aim of the webinars is to connect science and private industry, basic research with … Continued<\/a>\n <\/div>\n
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\n July 8, 2021\n <\/div>\n <\/div>\n <\/div>\n<\/article>
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\n \n \"meeting-of-the-CasProt-project-10-2020\"\n <\/a>\n <\/div>\n <\/div>\n
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UPJ\u0160 organized a Kick-off meeting for the CasProt project in October<\/h4>\n <\/a>\n
\n \n The kick-off meeting of the CasProt project was held by the Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice (UPJS) as a coordinator of the project Horizon 2020 from the European Framework Program of the EU for Research and Innovation within the framework of the “Twinning” call on the 12th and 13th of October 2020.\u00a0\u00a0 The objective … Continued<\/a>\n <\/div>\n
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\n October 25, 2020\n <\/div>\n <\/div>\n <\/div>\n<\/article> <\/div>\r\n <\/section>\r\n\r\n\r\n