{"id":19716,"date":"2025-09-12T14:45:39","date_gmt":"2025-09-12T14:45:39","guid":{"rendered":"https:\/\/www.upjs.sk\/pracoviska\/tip\/?post_type=cpt_aktuality&#038;p=19716"},"modified":"2025-09-23T14:51:21","modified_gmt":"2025-09-23T14:51:21","slug":"biochemistry-congress-2025","status":"publish","type":"cpt_aktuality","link":"https:\/\/www.upjs.sk\/pracoviska\/tip\/actuality\/biochemistry-congress-2025\/","title":{"rendered":"Biochemick\u00fd kongres 2025"},"content":{"rendered":"\n<p>Konferencia \u201eFEBS3+ Meeting: <a href=\"https:\/\/csbmb2025.cz\/\"><strong>XXVIII. BIOCHEMICK\u00dd KONGRES<\/strong><\/a> \u010ceskej a Slovenskej spolo\u010dnosti pre bioch\u00e9miu a molekul\u00e1rnu biol\u00f3giu s \u00fa\u010das\u0165ou Po\u013eskej a Nemeckej biochemickej spolo\u010dnosti\u201c s mottom \u201e<strong><em>Odha\u013eovanie tajomstiev \u017eivota<\/em><\/strong>\u201c sa konala v&nbsp;Prahe, v <em>N\u00e1rodn\u00ed technick\u00ed knihovne<\/em>, <strong>od 7. do 10. septembra 2025<\/strong> pri pr\u00edle\u017eitosti 70. v\u00fdro\u010dia zalo\u017eenia p\u00f4vodnej \u010ceskoslovenskej biochemickej spolo\u010dnosti.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"525\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-.jpg\" alt=\"\" class=\"wp-image-19718\" style=\"width:577px;height:auto\" srcset=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-.jpg 700w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress--300x225.jpg 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/figure>\n\n\n\n<p>Nieko\u013eko zamestnancov a doktorandov z Centra interdisciplin\u00e1rnych biovied TIP UPJ\u0160 v Ko\u0161iciach sa tejto konferencie z\u00fa\u010dastnilo aj osobne a akt\u00edvne. Za v\u0161etk\u00fdch spomenieme prof. RNDr. Erika Sedl\u00e1ka, DrSc., ktor\u00fd predniesol predn\u00e1\u0161ku \u201e<strong><em>Evolution of Haloalkane Dehalogenase by Ribosome Display<\/em><\/strong>\u201c, a Mgr. M\u00e1riu Tomkov\u00fa, PhD., ktor\u00e1 predstavila svoje v\u00fdsledky prostredn\u00edctvom posterovej prezent\u00e1cie s n\u00e1zvom \u201e<strong><em>Directed Evolution of Staphylokinase Improves Fibrinolytic Activity<\/em><\/strong>\u201c. Obaja tie\u017e predsedali sekci\u00e1m <em>Enz\u00fdmy<\/em> a <em>Biotechnol\u00f3gia<\/em>.<\/p>\n\n\n<style>.kb-row-layout-id19716_7053d6-7a > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id19716_7053d6-7a > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id19716_7053d6-7a > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:repeat(2, minmax(0, 1fr));}.kb-row-layout-id19716_7053d6-7a > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id19716_7053d6-7a > .kt-row-column-wrap{grid-template-columns:repeat(2, minmax(0, 1fr));}}@media all and (max-width: 767px){.kb-row-layout-id19716_7053d6-7a > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id19716_7053d6-7a alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column19716_0638ea-4e > .kt-inside-inner-col,.kadence-column19716_0638ea-4e > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column19716_0638ea-4e > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column19716_0638ea-4e > .kt-inside-inner-col{flex-direction:column;}.kadence-column19716_0638ea-4e > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column19716_0638ea-4e > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column19716_0638ea-4e{position:relative;}@media all and (max-width: 1024px){.kadence-column19716_0638ea-4e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column19716_0638ea-4e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column19716_0638ea-4e\"><div class=\"kt-inside-inner-col\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"525\" height=\"446\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-11.jpg\" alt=\"\" class=\"wp-image-19727\" style=\"width:556px;height:auto\" srcset=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-11.jpg 525w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-11-300x255.jpg 300w\" sizes=\"auto, (max-width: 525px) 100vw, 525px\" \/><\/figure>\n<\/div><\/div>\n\n\n<style>.kadence-column19716_3789be-f5 > .kt-inside-inner-col,.kadence-column19716_3789be-f5 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column19716_3789be-f5 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column19716_3789be-f5 > .kt-inside-inner-col{flex-direction:column;}.kadence-column19716_3789be-f5 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column19716_3789be-f5 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column19716_3789be-f5{position:relative;}@media all and (max-width: 1024px){.kadence-column19716_3789be-f5 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column19716_3789be-f5 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column19716_3789be-f5\"><div class=\"kt-inside-inner-col\">\n<p><\/p>\n\n\n\n<p>Oba pr\u00edspevky a v nich prezentovan\u00e9 v\u00fdsledky s\u00fa \u00fazko sp\u00e4t\u00e9 s realiz\u00e1ciou projektu APBC. <\/p>\n\n\n\n<p><strong>Prof. Sedl\u00e1k<\/strong> sa vo svojej predn\u00e1\u0161ke zameral na haloalk\u00e1nov\u00e9 dehalogen\u00e1zy \u2013 mikrobi\u00e1lne enz\u00fdmy, ktor\u00e9 rozkladaj\u00fa halogenovan\u00e9 uh\u013eovod\u00edky. Tieto enz\u00fdmy s\u00fa v\u00fdznamn\u00e9 v biotechnol\u00f3gi\u00e1ch, najm\u00e4 pre svoje vyu\u017eitie v biokatal\u00fdze, bioremedi\u00e1cii a pri odstra\u0148ovan\u00ed toxick\u00fdch l\u00e1tok z prostredia. Predstavil tie\u017e pokro\u010dil\u00e9 laborat\u00f3rne met\u00f3dy pou\u017e\u00edvan\u00e9 na CIB TIP UPJ\u0160 v Ko\u0161iciach, konkr\u00e9tne HaloTag technol\u00f3giu a riboz\u00f3mov\u00fd display, ktor\u00e9 umo\u017e\u0148uj\u00fa optimalizova\u0165 vybran\u00e9 varianty t\u00fdchto enz\u00fdmov s cie\u013eom z\u00edska\u0165 stabilnej\u0161ie formy s vy\u0161\u0161ou \u00fa\u010dinnos\u0165ou pri rozklade konkr\u00e9tnych l\u00e1tok.<\/p>\n<\/div><\/div>\n\n<\/div><\/div>\n\n\n<p>Poster <strong>dr. Tomkovej<\/strong> bol venovan\u00fd staphylokin\u00e1ze (SAK), bakteri\u00e1lnemu prote\u00ednu pou\u017e\u00edvan\u00e9mu ako liek na rozp\u00fa\u0161\u0165anie krvn\u00fdch zrazen\u00edn, ktor\u00fd sa be\u017ene vyu\u017e\u00edva pri lie\u010dbe trombotick\u00fdch ochoren\u00ed, ako je m\u0155tvica \u010di infarkt myokardu \u2013 hlavn\u00fdch pr\u00ed\u010din \u00famrt\u00ed na celom svete. Jeho klinick\u00e9 pou\u017eitie je v\u0161ak obmedzen\u00e9 imunitn\u00fdmi reakciami u pacientov. V r\u00e1mci projektu APBC preto vedci vyv\u00edjaj\u00fa neimunog\u00e9nne varianty SAK. Doteraj\u0161ie v\u00fdsledky nazna\u010duj\u00fa, \u017ee nov\u00e9 formy SAK m\u00f4\u017eu prinies\u0165 efekt\u00edvnej\u0161iu a bezpe\u010dnej\u0161iu trombolytick\u00fa terapiu, hoci ich stabilitu je potrebn\u00e9 \u010falej zlep\u0161ova\u0165.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"473\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-2-1024x473.jpg\" alt=\"\" class=\"wp-image-19724\" style=\"width:730px;height:auto\" srcset=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-2-1024x473.jpg 1024w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-2-300x139.jpg 300w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-2-768x355.jpg 768w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/24\/2025\/09\/Biochemistry-Congress-2.jpg 1083w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Konferencia \u201eFEBS3+ Meeting: XXVIII. BIOCHEMICK\u00dd KONGRES \u010ceskej a Slovenskej spolo\u010dnosti pre bioch\u00e9miu a molekul\u00e1rnu biol\u00f3giu s \u00fa\u010das\u0165ou Po\u013eskej a Nemeckej biochemickej spolo\u010dnosti\u201c s mottom \u201eOdha\u013eovanie tajomstiev \u017eivota\u201c sa konala v&nbsp;Prahe, v N\u00e1rodn\u00ed technick\u00ed knihovne, od 7. do 10. septembra 2025 pri pr\u00edle\u017eitosti 70. v\u00fdro\u010dia zalo\u017eenia p\u00f4vodnej \u010ceskoslovenskej biochemickej spolo\u010dnosti. Nieko\u013eko zamestnancov a doktorandov z Centra &hellip; <a href=\"https:\/\/www.upjs.sk\/pracoviska\/tip\/actuality\/biochemistry-congress-2025\/\">\u010c\u00edta\u0165 \u010falej<\/a><\/p>\n","protected":false},"author":16,"featured_media":19718,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[],"tax_aktuality":[361],"class_list":["post-19716","cpt_aktuality","type-cpt_aktuality","status-publish","has-post-thumbnail","hentry","tax_aktuality-361"],"acf":{"acf_link_na_externy_obsah":"","poradie_clanku":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Biochemick\u00fd kongres 2025 - Technologick\u00fd a inova\u010dn\u00fd park | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/pracoviska\/tip\/actuality\/biochemistry-congress-2025\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biochemick\u00fd kongres 2025 - Technologick\u00fd a inova\u010dn\u00fd park | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"Konferencia \u201eFEBS3+ Meeting: XXVIII. 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