{"id":83368,"date":"2025-11-28T16:03:40","date_gmt":"2025-11-28T15:03:40","guid":{"rendered":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/?post_type=cpt_aktuality&#038;p=83368"},"modified":"2026-04-09T15:17:14","modified_gmt":"2026-04-09T14:17:14","slug":"novy-chemosenzor-pre-loratadin-potencial-pre-uplatnenie-vo-farmaceutickej-analyze","status":"publish","type":"cpt_aktualne_spravy","link":"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/actual-news\/novy-chemosenzor-pre-loratadin-potencial-pre-uplatnenie-vo-farmaceutickej-analyze\/","title":{"rendered":"Nov\u00fd chemosenzor pre loratad\u00edn &#8211; potenci\u00e1l pre uplatnenie vo farmaceutickej anal\u00fdze"},"content":{"rendered":"<style>.kadence-column83368_443540-b3 > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kadence-column83368_443540-b3 > .kt-inside-inner-col,.kadence-column83368_443540-b3 > .kt-inside-inner-col:before{border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-right-radius:5px;border-bottom-left-radius:5px;}.kadence-column83368_443540-b3 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column83368_443540-b3 > .kt-inside-inner-col{flex-direction:column;}.kadence-column83368_443540-b3 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column83368_443540-b3 > .kt-inside-inner-col{background-color:#F4F4F4;}.kadence-column83368_443540-b3 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column83368_443540-b3{position:relative;}@media all and (max-width: 1024px){.kadence-column83368_443540-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column83368_443540-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column83368_443540-b3\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-justify\">Farmaceutick\u00e9 l\u00e1tky \u010dasto obsahuj\u00fa sekund\u00e1rne alebo terci\u00e1rne aminoskupiny, alebo in\u00e9 skupiny obsahuj\u00face dus\u00edk. V&nbsp;kyslom prostred\u00ed s\u00fa schopn\u00e9 proton\u00e1cie za vzniku kladne nabit\u00fdch i\u00f3nov, ktor\u00e9 vytv\u00e1raj\u00fa stabiln\u00e9 i\u00f3nov\u00e9 asocia\u010dn\u00e9 komplexy (IAC) s ur\u010dit\u00fdmi ani\u00f3nov\u00fdmi formami organick\u00fdch farb\u00edv. To je z\u00e1kladn\u00fd predpoklad v\u00fdvoja spektrofotometrick\u00fdch a luminiscen\u010dn\u00fdch met\u00f3d. Medzi tak\u00e9to l\u00e1tky patr\u00ed aj loratad\u00edn. Loratid\u00edn je dlhodobo p\u00f4sobiace antihistaminikum druhej gener\u00e1cie, ktor\u00e9 sa pou\u017e\u00edva na zmiernenie alergick\u00fdch pr\u00edznakov. Je to v\u010faka jeho \u00fa\u010dinku ako selekt\u00edvneho antagonistu histam\u00ednov\u00fdch H1 receptorov.<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<style>.kadence-column83368_6be924-b0 > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kadence-column83368_6be924-b0 > .kt-inside-inner-col,.kadence-column83368_6be924-b0 > .kt-inside-inner-col:before{border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-right-radius:5px;border-bottom-left-radius:5px;}.kadence-column83368_6be924-b0 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column83368_6be924-b0 > .kt-inside-inner-col{flex-direction:column;}.kadence-column83368_6be924-b0 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column83368_6be924-b0 > .kt-inside-inner-col{background-color:#F4F4F4;}.kadence-column83368_6be924-b0 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column83368_6be924-b0{position:relative;}@media all and (max-width: 1024px){.kadence-column83368_6be924-b0 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column83368_6be924-b0 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column83368_6be924-b0\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-column-wrap{grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id83368_6e6e0a-e4 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id83368_6e6e0a-e4 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-left-golden kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column83368_ead02d-d7 > .kt-inside-inner-col,.kadence-column83368_ead02d-d7 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column83368_ead02d-d7 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column83368_ead02d-d7 > .kt-inside-inner-col{flex-direction:column;}.kadence-column83368_ead02d-d7 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column83368_ead02d-d7 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column83368_ead02d-d7{position:relative;}@media all and (max-width: 1024px){.kadence-column83368_ead02d-d7 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column83368_ead02d-d7 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column83368_ead02d-d7\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-justify\"><strong><a class=\"has-text-align-justify\"><strong>Prof. Andrii Vyshnikin, PhD.<\/strong><\/a><\/strong> a kolekt\u00edv z&nbsp; <strong>Katedry analytickej ch\u00e9mie <\/strong><a href=\"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/pracoviska\/ustavy-pf\/uchv\/\"><strong>\u00dastavu chemick\u00fdch vied<\/strong><\/a> sa vo svojej pr\u00e1ci zamerali na v\u00fdvoj nov\u00e9ho kolorimetrick\u00e9ho senosora pre selekt\u00edvne stanovenie loratid\u00ednu. Pr\u00e1ca predstavuje nov\u00fd pr\u00edstup vo v\u00fdvoji bezextrak\u010dn\u00fdch spektrofotometrick\u00fdch met\u00f3d zalo\u017een\u00fdch na i\u00f3nov\u00fdch asoci\u00e1toch ani\u00f3nov\u00fdch farb\u00edv s protonovan\u00fdmi formami lie\u010div obsahuj\u00facich dus\u00edk. Bola \u00faspe\u0161ne aplikovan\u00e1 na stanovenie loratid\u00ednu vo farmaceutick\u00fdch pr\u00edpravkoch a z\u00edskan\u00e9 v\u00fdsledky nazna\u010duj\u00fa, \u017ee t\u00e1to met\u00f3da m\u00e1 ve\u013ek\u00fd potenci\u00e1l pre uplatnenie vo farmaceutickej anal\u00fdze. Uveden\u00e1 pr\u00e1ca bola navy\u0161e prezentovan\u00e1 aj na titulnej strane \u010dasopisu <em><strong>Chemosensors (<\/strong><\/em><strong>JCR&nbsp;&#8211;&nbsp;Q2 Instruments and Instrumentation; Q1 Physical and Theoretical Chemistry).<\/strong><\/p>\n\n\n\n<p><strong><u>Vishnikin, A.B.<\/u><\/strong>, Chernyavskaya, A., <strong>Bazel. Y.<\/strong> <em>Colorimetric chemosensor for determination of loratadine based on bromocresol purple\u2013cationic polyacrylamide copolymer system.<\/em> <em>Chemosensors<\/em><strong> <\/strong><em>13<\/em>(10) (<strong>2025)<\/strong> 357, DOI: <a href=\"https:\/\/www.mdpi.com\/2227-9040\/13\/10\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.mdpi.com\/2227-9040\/13\/10<\/a>.<\/p>\n<\/div><\/div>\n\n\n<style>.kadence-column83368_e030c9-00 > .kt-inside-inner-col,.kadence-column83368_e030c9-00 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column83368_e030c9-00 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column83368_e030c9-00 > .kt-inside-inner-col{flex-direction:column;}.kadence-column83368_e030c9-00 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column83368_e030c9-00 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column83368_e030c9-00{position:relative;}@media all and (max-width: 1024px){.kadence-column83368_e030c9-00 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column83368_e030c9-00 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column83368_e030c9-00\"><div class=\"kt-inside-inner-col\"><style>.kb-image83368_05790e-d6 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image83368_05790e-d6 size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"627\" height=\"900\" src=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2025\/11\/akt-UCHV-Chemosensors-12112025.png\" alt=\"\" class=\"kb-img wp-image-83371\" srcset=\"https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2025\/11\/akt-UCHV-Chemosensors-12112025.png 627w, https:\/\/www.upjs.sk\/app\/uploads\/sites\/10\/2025\/11\/akt-UCHV-Chemosensors-12112025-209x300.png 209w\" sizes=\"auto, (max-width: 627px) 100vw, 627px\" \/><\/figure>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<style>.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col,.kadence-column83368_ff57ea-96 > .kt-inside-inner-col:before{border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-right-radius:5px;border-bottom-left-radius:5px;}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{flex-direction:column;}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{background-color:#F4F4F4;}.kadence-column83368_ff57ea-96 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column83368_ff57ea-96{position:relative;}@media all and (max-width: 1024px){.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column83368_ff57ea-96 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column83368_ff57ea-96\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-justify\">T\u00e1to pr\u00e1ca bola financovan\u00e1 programom E\u00da NextGenerationEU, prostredn\u00edctvom Pl\u00e1nu obnovy a odolnosti pre Slovensko (09I03-03-V01-00106).<a href=\"https:\/\/www.upjs.sk\/PF\/zamestnanec\/andrii.vyshnikin\/\"><strong>Prof. Andrii Vyshnikin, PhD.<\/strong><\/a> p\u00f4sob\u00ed na <a href=\"https:\/\/analyticalchemistry.science.upjs.sk\/\"><strong>Katedre analytickej ch\u00e9mie<\/strong><\/a><strong> UCHV PF UPJ\u0160. <\/strong>Venuje sa spektroskopick\u00fdm met\u00f3dam a zameriava na v\u00fdvoj optick\u00fdch a&nbsp;elektrochemick\u00fdch senzorov. Vo svojej v\u00fdskumnej pr\u00e1ci rozv\u00edja met\u00f3dy mikroextrakcie ako aj prietokov\u00e9 met\u00f3dy pre stanovenie i\u00f3novo asociovan\u00fdch komplexov. Je autorom pribli\u017ene 390 publik\u00e1ci\u00ed, z toho 76 \u010dl\u00e1nkov evidovan\u00fdch v&nbsp;datab\u00e1zach Scopus a&nbsp;Web of Science s&nbsp;vy\u0161e 560 cit\u00e1ciami. Pod jeho veden\u00edm bolo obh\u00e1jen\u00fdch 15 dizerta\u010dn\u00fdch pr\u00e1c.<\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>V\u00fdsledky v\u00fdskumnej pr\u00e1ce prof. Andriya B Vishnikina a kolekt\u00edvu z  Katedry analytickej ch\u00e9mie \u00daCHV nazna\u010duj\u00fa, \u017ee met\u00f3da ktor\u00fa \u00faspe\u0161ne aplikovali na stanovenie loratid\u00ednu vo farmaceutick\u00fdch pr\u00edpravkoch m\u00e1 ve\u013ek\u00fd potenci\u00e1l pre uplatnenie vo farmaceutickej anal\u00fdze.<\/p>\n","protected":false},"author":25,"featured_media":83379,"menu_order":0,"template":"","meta":{"_acf_changed":false},"categories":[],"tags":[63],"tax_aktuality":[],"class_list":["post-83368","cpt_aktualne_spravy","type-cpt_aktualne_spravy","status-publish","has-post-thumbnail","hentry","tag-uchv"],"acf":{"acf_link_na_externy_obsah":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nov\u00fd chemosenzor pre loratad\u00edn - potenci\u00e1l pre uplatnenie vo farmaceutickej anal\u00fdze - Pr\u00edrodovedeck\u00e1 fakulta | UPJ\u0160<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.upjs.sk\/prirodovedecka-fakulta\/actual-news\/novy-chemosenzor-pre-loratadin-potencial-pre-uplatnenie-vo-farmaceutickej-analyze\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nov\u00fd chemosenzor pre loratad\u00edn - potenci\u00e1l pre uplatnenie vo farmaceutickej anal\u00fdze - Pr\u00edrodovedeck\u00e1 fakulta | UPJ\u0160\" \/>\n<meta property=\"og:description\" content=\"V\u00fdsledky v\u00fdskumnej pr\u00e1ce prof. 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