From 17 to 21 November 2025, researchers from the Center for Interdisciplinary Biosciences (CIB, UPJŠ) visited the University of Debrecen to further strengthen their collaboration with the team of Dr. György Vámosi. The visit brought together Dr. Veronika Huntošová and Dr. Ľuboš Ambro to advance joint research on fluorescent proteins for bioimaging and targeted cancer therapy.
The visit was carried out within the ABPC project (09I02-03-V01-00021), funded by the EU Recovery and Resilience Plan and coordinated by UPJŠ. The project aims to develop advanced protein biotechnology in Eastern Slovakia and to build strong international research links. During the stay, Dr. Ambro presented modern protein evolution and engineering approaches with direct applications in biotechnology and biomedical research. A key outcome of the ABPC-supported visit was the establishment of a new collaborative framework for recombinant protein production in Sf9 insect cells, including advanced cloning strategies and detailed biochemical and biophysical characterization. This cooperation significantly strengthens the technological base and international impact of the ABPC project.
As part of Dr. Huntošová’s canSERV project (funded under the Horizon Europe programme, grant agreement No. 101058620) on HER2-targeted breast cancer treatment, advanced imaging experiments were performed at the Cellular Imaging Hungary Node in Debrecen, Hungary, as part of Euro-BioImaging. Using FLIM, high-resolution fluorescence microscopy and electron microscopy, the researchers studied the behavior of the AsLOV2 fluorescent fusion protein in cancer cells.
One of Dr. Huntošová’s main research goals is the development of targeted delivery systems for cancer therapy. Using advanced bioimaging, her team studies their interaction with cancer cell receptors and the resulting ultrastructural cellular responses. This work is conducted within the BCOrgFluorIDA project (09I03-03-V04-00007), supported by EU NextGenerationEU through the Recovery and Resilience Plan for Slovakia.
